FSS Resveratrol Bioferment PF

INCI: Aqua & Pichia/Resveratrol Ferment Extract & Leuconostoc/Radish Root Ferment Filtrate

Use Levels: 1.0% - 5.0%

Solubility: Water Soluble 

Appearance: Clear to Hazy Liquid
pH (as-is @ 25°C): 3.5 - 6.5
Total Protein (BCA Assay): > 0.5 mg/mL

BACKGROUND

Resveratrol became a subject of interest for scientists when found to be present in red wine, leading to speculation as a possible explanation for the "French Paradox”. The rich assortment of phytonutrients found in grapes which include anthocyanins, flavonoids, saponins and polyphenols, is thought to be responsible for the numerous protective effects on cholesterol metabolism, inflammation, and oxidative stress. Studies have shown that resveratrol is capable of providing anti-cancer, anti-viral, anti-aging and anti-inflammatory effects. Antioxidant activity is another key benefit of resveratrol.

FSS Resveratrol Bioferment PF is produced through the fermentation of yeast, Pichia pastoris, which converts resveratrol into more bioavailable intermediates. Pichia pastoris belongs to the genus Saccharomycetase and is closely related to Saccharomyces cerevisiae. Like Saccharomyces, the microorganism has distinctive abilities to express bio-actives that are capable of unique benefits, without application of human cell lines. From a formulating point of view, Pichia pastoris also affords the unique affinity for lipid based compounds, and therefore acts as a model organism for biofermentation of oil soluble or insoluble actives, and an ideal choice to advance the natural discovery of skin care actives.

The proprietary growth conditions allow the yeast to utilize the small molecule, resveratrol, during growth. During feeding, the cells are actively replicating, allowing utilization of the small molecule. Several growth and fermentation parameters are monitored during the growth phase of the yeast to ensure the viability of the cells and complete utilization of resveratrol. Pichia pastoris utilizes resveratrol as a nutrient and by-metabolization, the yeast convert the resveratrol into more bioavailable intermediates. Upon completion of the fermentation process, the composition is filtered and the extract is isolated.

FSS Resveratrol Bioferment PF was developed to capitalize on the benefits associated with resveratrol in cosmetic formulations. Resveratrol has been well recognized for promoting collagen synthesis, enhancing skin tone, skin lightening, and anti-aging benefits.

Storage: Protected from direct light and humidity at a temperature not exceeding 32°C.

Shelf life: 12 months, properly stored, in sealed container. Based on stability studies, the optimum storage temperature for maximization of shelf life is 23 - 25°C.

**This product should be added to a formulation at the recommended usage rate**